Dopamine
catecholamine-vasoconstrictor
(dopaminergic, beta and alpha
receptors)
Rember to fill the tank.
Mix 200 or 400 mg in 500 mg of D5W.
Premix= 400mg/250cc D5W
Hemodynamically significant hypotension:
low dose-
1-2 mcg/kg/min=cerebral, mesenteric and renal vasodilation; UOP
increase; HR & BP unchanged
mid dose- 2-10 mcg/kg/min= increased cardiac output
high dose- >10mcg/kg/min=
increased SVR, PVR, preload
secondary to renal, mesenteric,
peripheral arterial and venous
vasoconstriction
toxic dose- >20mcg/kg/min
ischemic changes
Symptomatic bradycardia- add
norepinephrine if > 20mcg/kg/min
required
If infiltrates use regitine phentolamine. Give multiple 1ml
iniections SQ in a circle around area of infiltration.
Ehould be given via central line.
* Use lowest dose that produces desired effect
* Avoid in hypovolemia, high SVR, pulmonary congestion or
increased preload
* Avoid Na Bicarb line
* Avoid extravasation
* MAO inhibitors potentiate effects